Searchable abstracts of presentations at key conferences on calcified tissues

ba0002op14 | (1) | ICCBH2013

Inflammation and glucocorticoid therapy impair skeletal modeling during growth following crohn disease diagnosis

Tsampalieros Anne , Shults Justine , Zemel Babette , Baldassano Robert , Leonard Mary

Objectives: Examine changes in volumetric BMD and cortical structure following Crohn Disease (CD) diagnosis, and identify associations with growth, glucocorticoid exposure and disease activity.Methods: Prospective cohort study in 76 CD participants, ages 5–21 years. Tibia pQCT scans were obtained at diagnosis, 6, 12 and a median of 42 months later. Sex, race and age-specific Z-scores were generated based on >650 controls. Cortical dimen...